SUDS project

Machine Learning for Healthcare

Research description:

The SUDS Scholar will develop and apply machine learning models and algorithms to solve predictive problems in healthcare. There are a variety of ongoing projects in the lab that they may be assigned to based on their research interest. Below is a description of two ongoing projects in the lab.

a) Identifying patients at highest risk of dying on the liver transplant waitlist both across the United States and in Toronto. This project will leverage large datasets (~100K patients in the US and ~2K patients in Canada) to identify patterns in longitudinal (time-varying) clinical biomarkers that are predictive of patient mortality in order to help clinicians, patients and hospital systems make more informed choices on allocating livers. The models developed will be assessed to ensure their predictive performance is equitable across various patient subgroups.

b) GEMINI is a large scale dataset of clinical data from patients in hospitals across Ontario. Our group is building tools to create statistical guardrails to understand and assess the fairness, trustworthiness and the failure modes of predictive risk scores used in different hospitals.

The SUDS Scholar will be paired with a graduate student mentor who will work with them to provide additional guidance, support and mentorship during the summer internship.

Year: 2023

Researcher:
Rahul Krishnan, Department of Computer Science, Faculty of Arts & Science,  University of Toronto

Student: 
Junlong Zhang, University of Toronto

Through SUDS, undergraduate students engage in hands-on research focused on data sciences and AI methodology applications.

Learning Analytics for Improved Design of Programs of Study

Research description:

Learning analytics involves the collection and analysis of student and course data, including interactions with educational technology such as a learning management system (LMS), for the purposes of better understanding and optimizing student learning and learning environments. Most investigations of student engagement have focused on the course-level activity analysis. However, this project will investigate whether the analysis of engagement across courses and academic terms may inform program-level practices in learning design that can benefit all students.

The project will involve identifying, visualizing and analyzing LMS and administrative data from the University of Toronto to investigate how the data might effectively be used to identify student patterns of activity across courses and academic terms. Possible questions that could be considered include: Are there patterns of student activity across courses that appear to be productive and patterns that do not? How do these patterns vary with student program of study or prerequisite courses? Can LMS activity data be used as a proxy for student engagement across courses taken concurrently? What program-level aspects are related to changes in a student’s odds of dropping out of a course? The particular question will be determined based on the interests and background of the SUDS Scholar.

Year: 2023

Researcher:
Alison Gibbs, Department of Statistical Sciences, Faculty of Arts & Science, University of Toronto

Student: 
Ke Shi, University of Toronto

Through SUDS, undergraduate students engage in hands-on research focused on data sciences and AI methodology applications.

Land market frictions in India and historical housing discrimination and zoning in North America

Research description:

The SUDS Scholar will be studying historic factors and current policies associated with land and urban development and their effects on growth and social inequality. They will employ a broad range of research techniques, often combining theoretical and empirical methodologies to answer policy-relevant economic questions using detailed micro-data. In particular, they will work with historical data, tax assessor data, geo-coded spatial data, and administrative firm data.

Year: 2023

Researcher:
Aradhya Sood, Department of Management, University of Toronto Scarborough

Student: 
Xiaofeng Liu, University of Toronto

Through SUDS, undergraduate students engage in hands-on research focused on data sciences and AI methodology applications.

Integrative Supervised Machine Leaning Model for Cancer Risk Stratification

Research description:

The SUDS Scholar will utilize multi-modal molecular and imaging data to build machine learning framework for cancer risk stratification.

Year: 2023

Researcher:
Sushant Kumar, Princess Margaret Cancer Centre, University Health Network

Student: 
Jackson Howe, University of Waterloo

Through SUDS, undergraduate students engage in hands-on research focused on data sciences and AI methodology applications.

Identification of progenitor cell populations from human pluripotent stem cell derived fetal lung cells

Research description:

In human PSC differentiation towards lung epithelial cell phenotypes, a heterogenous population of progenitor cells emerge in culture that seemingly gives rise to different cell types. However, to better understand this, isolation of these progenitor cells is required to functionally and phenotypically interrogate their developmental potential. The SUDS Scholar will analyze single cell RNA sequencing datasets generated in the lab to computationally determine the expression of unique cell surface molecules that can be used to isolate each progenitor population for validation. The SUDS Scholar will get to use their computational skills to analyze large datasets to help identify new cells/genotype/phenotypes and GRN regulating human-specific developmental or disease mechanisms.

Year: 2023

Researcher:
Amy Wong, Developmental & Stem Cell Biology Labs, SKH

Student: 
Aerin Wang, University of Toronto

Through SUDS, undergraduate students engage in hands-on research focused on data sciences and AI methodology applications.